Scientists Unlock Key to Stronger CAR T Cancer Fighters
Photo: Kelly Sikkema / Unsplash
Researchers have identified a protein called NFIL3 that causes engineered immune cells to weaken over time, limiting their cancer-fighting effectiveness. By disabling this protein, scientists were able to keep the cells stronger and more powerful for longer periods. In animal models, this breakthrough approach controlled tumors significantly more effectively, opening promising new possibilities for improving CAR T-cell therapy.
Researchers have identified a protein called NFIL3 that causes engineered immune cells to weaken over time, limiting their cancer-fighting effectiveness. By disabling this protein, scientists were able to keep the cells stronger and more powerful for longer periods. In animal models, this breakthrough approach controlled tumors significantly more effectively, opening promising new possibilities for improving CAR T-cell therapy.